Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLYQYHCACCDKVV-----A-STDKSCPYCGSHHIRSPYGLWMFCVMACLAVVVVFKVVHLYIQNHQDTPVQSTLLDVLNEGDKSTKQ 2Y0S Chain:P ((4-39)) ----YRCGKCWKTFTDEQLKVLPGVRCPYCGYKIIFMVRK------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2Y0S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain P - contact count / total energy / energy per contact / energy per residue : 70 -4345 -62.07 -144.83 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain P : 0.51 3D Compatibility (PKB) : -62.07 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.51 QMean score : 0.670

(partial model without unconserved sides chains): PDB file : Tito_2Y0S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Y0S-query.scw PDB file : Tito_Scwrl_2Y0S.pdb: