Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVIALFSKNWSRTMSATIVNTTDDNFQADVLDAETPVLVDFWAGWCAPCKAIAPVLEDLSSEYAGKVKIVKVDVTSCEETAVKYNIRNIPALLLFKNGEVVAQQIGAVPRSKLVSFIDENV 5HR2 Chain:A ((2-108)) --------------SDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGAASKGQLKEFLDANL

General information: TITO was launched using: RESULT: Template: 5HR2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 482 -81893 -169.90 -765.35 target 2D structure prediction score : 0.77 Monomeric hydrophicity matching model chain A : 0.82 3D Compatibility (PKB) : -169.90 2D Compatibility (Sec. Struct. Predict.) : 0.77 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.818

(partial model without unconserved sides chains): PDB file : Tito_5HR2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5HR2-query.scw PDB file : Tito_Scwrl_5HR2.pdb: