Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKSTSTTSITNTSTGN--------VDSQHSQSSIQSFSISSTSEM----QESTVPSLPLENSDKALLFLIAHRSELQSDDIVISFYQKIDRDYLFTASSKQ-----IRSQGGSGSVGFYRVSPEGSITMTDANGTPF 1OM6 Chain:A ((168-303)) -----------------------------------THEIGHTLGLSHPGD------NPTYRDAVYAEDTRAYSVMSYWSEKNTGQVFTKTGEGAYASAPLLDDIAAVQKLYGANLETRADDTVYGFNSTADRDFYSATSSTDKLIFSVWDGGGNDTLDFSGFSQNQKINLT-------

General information: TITO was launched using: RESULT: Template: 1OM6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 440 19775 44.94 175.00 target 2D structure prediction score : 0.35 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 44.94 2D Compatibility (Sec. Struct. Predict.) : 0.35 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.237

(partial model without unconserved sides chains): PDB file : Tito_1OM6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1OM6-query.scw PDB file : Tito_Scwrl_1OM6.pdb: