Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKVVVIGCTHAGTAAVKSILKNHPEA-EVTVYERNDNISFLSCGIALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETVSYDKLVMTTGSWPIIPPISGIDAK-----------NVLLCKNYNQANEIIAQA--KEAKRVVIVGGGYIGIELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITDEEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDIFAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGWTIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTE-KVMMELVYEKGTNRIVGAQFMSKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ 2BCP Chain:A ((37-488)) -KIVVVGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGSGMALWIGEQIAGPEGLFYSDKEELESLGAKVYMESPVQSIDYDAKTVTA--LVDGKNHVETYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVIAKLENKDIKRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQLAFGETVKEVAGN--GKVEKIITDKNEYDVDMVILAVGFRPNTTLGNGKIDLFRNGAFLVNKRQETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTDLEGIGVQGSNGISIYGLHMVSTGLTLEKAKRLGFDAAVTEYTDNQKPEFIEHGNFPVTIKIVYDKDSRRILGAQMAAREDVSMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMAALGA--------

General information: TITO was launched using: RESULT: Template: 2BCP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2609 18118 6.94 41.46 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.83 3D Compatibility (PKB) : 6.94 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.531

(partial model without unconserved sides chains): PDB file : Tito_2BCP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2BCP-query.scw PDB file : Tito_Scwrl_2BCP.pdb: