Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTAIANNHVVSFHYKLTNAEGETLDQSQGEPLAYLHGAGNIIPGLENALTGKTVGDKFTVNVPAAEGYGEYNPDLVQEVPAQMFQGVDNIQPGMQFQAQTDDG-VQIVTVKAVEGDNVIVDANFPLAGQDLTFEVEIVEIREASQEELDHGHVHGAGGHHH 4ODM Chain:C ((2-147)) --KVGQDKVVTIRYTLQV-EGEVLDQ---GELSYLHGHRNLIPGLEEALEGREEGEAFQAHVPAEKAYGPHDPEGVQVVPLSAFPEDAEVVPGAQFYAQDMEGNPMPLTVVAVEGEEVTVDFNHPLAGKDLDFQVEVVKVREATPEELLHGH---------

General information: TITO was launched using: RESULT: Template: 4ODM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 588 -23592 -40.12 -162.70 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain C : 0.80 3D Compatibility (PKB) : -40.12 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.615

(partial model without unconserved sides chains): PDB file : Tito_4ODM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ODM-query.scw PDB file : Tito_Scwrl_4ODM.pdb: