Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGSYISPRITFPGLHELVRHY 4U17 Chain:A ((6-88)) WYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHY

General information: TITO was launched using: RESULT: Template: 4U17.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 243 -10937 -45.01 -131.77 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.93 3D Compatibility (PKB) : -45.01 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.93 QMean score : 0.504

(partial model without unconserved sides chains): PDB file : Tito_4U17.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4U17-query.scw PDB file : Tito_Scwrl_4U17.pdb: