Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MREKMRFPTLVFDIETLTDLKAGAHLYHLDLPEADVEQALTKIRRQESGMDFQRLPLHEIVCISGLWIDESGFRLFSFSREHYSEAEILQKFLSIFDKRHP-TLVSWNGSQFDLPVILFRAMYHGLSAPGLFDQGELDSQKRFNNY-------QNRYH-HRHIDLMDVMAMF--NGRNFQKLDDVACILGLPGKR-GES---GYHVPEYVRTEQWLKLTSYCEGDVLNTWFIYLRWLLLKGQMNVDEHNHWISSSIEYLQTMPQQADFLEVWQRTSKHTEFTSHYFNPLNF 3K57 Chain:A ((201-353)) ---------------------------------------------------------------------------------VASRPQLLEKLNAWFANYDPDVIIGWNVVQFDLRMLQKHAERYRLPLRLGRD--N--SELEWREHGFKNGVFFAQAKGRLIIDGIEALKSAFWNFSS-FSLETVAQELLGEGKSIDNPWDRMDEIDRRFAE-DKPALATYNLKNCELVTQIFHKTEIMP---------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3K57.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 390 1144 2.93 8.29 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain A : 0.58 3D Compatibility (PKB) : 2.93 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.58 QMean score : 0.357

(partial model without unconserved sides chains): PDB file : Tito_3K57.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3K57-query.scw PDB file : Tito_Scwrl_3K57.pdb: