Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKES----------------QVYLLGTGLRGKEDFLSVSDIIDYF 1JU5 Chain:A ((2-93)) WYWGRLSRQEAVALLQG-QRHGVFLVRDSS--TSPGDYVLSVSENSRVSHYIINSSGPRPPVPPSPAQPPPGVSPSRLRIG-----DQEFDSLPALLEFY

General information: TITO was launched using: RESULT: Template: 1JU5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 216 -27374 -126.73 -360.18 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -126.73 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.596

(partial model without unconserved sides chains): PDB file : Tito_1JU5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JU5-query.scw PDB file : Tito_Scwrl_1JU5.pdb: