Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WYHGAIPRAEVAELLV---HSGDFLVRESQGKQ-EYVLSVLWDGLPRHFIIQAHAPSEWRLLT 1FYR Chain:D ((13-63)) WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKV------------

General information: TITO was launched using: RESULT: Template: 1FYR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 146 2923 20.02 62.19 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain D : 0.75 3D Compatibility (PKB) : 20.02 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.665

(partial model without unconserved sides chains): PDB file : Tito_1FYR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1FYR-query.scw PDB file : Tito_Scwrl_1FYR.pdb: