Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDGLGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRFTLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDTIVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGLRGSKASVNKFKPDLFFAVDCSAADDTVTKNGT-FGHLGEGTLMRIQDPGLIMLPRLREYLLDIAETNNIPYQYFVSK-GGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFEAAREMLIQTLKGLDKSTVNTIVYGK 1YLO Chain:D ((3-343)) --AMDLSLLKALSEADAIASSEQEVRQILLEEAARLQKEVRFDGLGSVLIRLNES--TGPKVMICAHMDEVGFMVRSISREGAIDVLPVGNVRMAARQLQPVRITTREECKIPGLLDG---------DR-QGNDVSAMRVDIGARTYDEVMQAGIRPGDRVTFDTTFQVLP-HQRVMGKAFDDRLSCYLLVTLLRELHDAELPAEVWLVASSSEEVGLRGGQTATRAVSPDVAIVLDTACWAKNFDYGAANHRQIGNGPMLVLSDKSLIAPPKLTAWIETVAAEIGVPLQADMFSNGGTDGGAVHLTGTGVPTLVMGPATRHGHCAASIADCRDILQMEQLLSALIQRLTRETVVQ-----

General information: TITO was launched using: RESULT: Template: 1YLO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 2055 -124836 -60.75 -368.25 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain D : 0.76 3D Compatibility (PKB) : -60.75 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.482

(partial model without unconserved sides chains): PDB file : Tito_1YLO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1YLO-query.scw PDB file : Tito_Scwrl_1YLO.pdb: