Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKLVFVCLGNICRSPMAEFVMKSMTDN-------YEIQSRATSSWEHGNPIHKGTQGIFQQYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDKIYSFS---------SESVPDPWYTG--DFEETYRRVQEGCQAWLERLEKES 1D1Q Chain:A ((7-160)) KISVAFIALGNFCRSPMAEAIFKHEVEKANLENRFNKIDSFGTSNYHVGESPDHRTVSICKQHGVKIN--HKGKQIKTKHFDEYDYIIGMDESNINNLKKIQPEGSKAKVCLFGDWNTNDGTVQTIIEDPWYGDIQDFEYNFKQITYFSKQFLKKE----

General information: TITO was launched using: RESULT: Template: 1D1Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 631 -2522 -4.00 -18.54 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : -4.00 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.613

(partial model without unconserved sides chains): PDB file : Tito_1D1Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1D1Q-query.scw PDB file : Tito_Scwrl_1D1Q.pdb: