Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNIVQDKNMLPDDQWIDVCALDDLTPNTGAGALVGGQAVAIFRVGHEKRVYVLSNKDPFSQANVMSRGIIGDLQGERVVASPIYKQHFSLATGRCLEDKDQKLAVYPSKIVDGRVWVNAVPQKTYITNTGVSQDKLRLVLIGNGLAGMRCLEDLLDMVPDRYEVTVIGEEPWGNYNRIMLS-PVLSGEKTIEDIMLHPPKWYDDKGIKFIAGDKAVKIDRPRKVVYTEKGQTVDYDRLILATGSAPFIPPVQGVDLKGVLTFRDIYDVNTMIEYCG-SKNNAVVIGGGLLGLEAAYGLKQRGMNVTVLHLMDRIMERQLDGRASQLLRHSIEQKGIQIITEANTEALIGDENGHVKQIRLKDGTVLDADLVVFAVGIRPNIALAQSAGLRCNRGVLVNDTMQTFDPSIYAVGECIEHRGQT-------FGLVEPLWGQAFICATHLAEHGSLTFKAPTVPTQLKVSGVDVFSAGNFEPKDDYEDIILNDEKRQIYKRIIIQNDRVIGAVLFGDTEDGMWYAELIADQTPVSSFRNKLLFGRDFALKNAG 3LXD Chain:A ((7-400)) ------------------------------------------------------------------------------------------------------------------------------------AERADVVIVGAGHGGAQAAIALRQNGF-EGRVLVIGREPEIPYERPPLSKEYLAREKTFERICIRPAQFWEDKAVEMKLGAEVVSLDPAAHTVKLGDGSAIEYGKLIWATGGDPRRLSCVGADLAGVHAVRTKEDADRLMAELDAGAKNAVVIGGGYIGLEAAAVLTKFGVNVTLLEALPRVLARVAGEALSEFYQAEHRAHGVDLRTGAAMDCIEGDG-TKVTGVRMQDGSVIPADIVIVGIGIVPCVGALISAGASGGNGVDVDEFCRTSLTDVYAIGDCAAHANDFADGAVIRLESVQNANDMATAAAKDICGA-PVPYKATP-WFWSNQYDLKLQTVGLSTGH--DNAVLRGDPATRSFSVVYLKGGKVVALDCVNMVKDYVQGKKLVEARAQIAP-----------------

General information: TITO was launched using: RESULT: Template: 3LXD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2325 -37014 -15.92 -96.14 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -15.92 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.568

(partial model without unconserved sides chains): PDB file : Tito_3LXD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3LXD-query.scw PDB file : Tito_Scwrl_3LXD.pdb: