Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRIILLGPPGAGKGTQAQLICKRYNIPQISTGDMLRAAIREGTELGLKAKSVMESGGLVSDELIIGLVKERIAQPDCVNGCIFDGFPRTIPQAEALEKE----GISIDHVIEIDVPDEEIVKRLSGRRQHPASGRVYHVVYNPPKVEGKDDETGEDLVQRPDDQEETIRKRLASYHTETEQLVGFYQGRAASGENAPTYDKLDGLRTIEDVQKDLFNILDK 4MKH Chain:A ((3-214)) MNIVLMGLPGAGKGTLAEKIVEKYGIPHISTGDMFRAAMKEETPLGLEAKSYIDKGELVPDEVTIGIVRERLSKSDCERGFLLDGFPRTVAQAEALEEILEEMGRPIDYVINIQVRKEELMERLTGRRICSVCGTTYHLVFNPPKTPGICDKDGGELYQRADDNEETVTKRLEVNMKQMAPLLAFYDSKEV-------LVNVNGERDIEDVFADVDVIL--

General information: TITO was launched using: RESULT: Template: 4MKH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 945 -47831 -50.61 -229.96 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain A : 0.84 3D Compatibility (PKB) : -50.61 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.84 QMean score : 0.526

(partial model without unconserved sides chains): PDB file : Tito_4MKH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MKH-query.scw PDB file : Tito_Scwrl_4MKH.pdb: