Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTISLVYISLSGNTESFVTRLKDYLLSQYKRIEVQKIHIKDLVKEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYG------NNASKCFGVVGSGNRNFNNQYCLTAKQYSQRFG---FPVLA-DFEMRGMLE-DIKHVAAIIADLYELEKEN 3F6R Chain:B ((2-148)) -SKVLIVFGSSTGNTESIAQKLEELIAAG--GHEVTLLNAADASA--ENLADGYDAVLFGCSAWGME-----------DLEMQDDFLSLFEEFDRIGLAGRKVAAFASGDQEYE-HFCGAVPAIEERAKELGATIIAEGLKMEGDASNDPEAVASFAEDVLKQL---

General information: TITO was launched using: RESULT: Template: 3F6R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 731 -42532 -58.18 -312.74 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain B : 0.74 3D Compatibility (PKB) : -58.18 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.402

(partial model without unconserved sides chains): PDB file : Tito_3F6R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3F6R-query.scw PDB file : Tito_Scwrl_3F6R.pdb: