Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTVTTYIGLGSNLGDSRQILSEAITKLKSLGEVKVSKL---YQSPPMGPQDQPNYLNAVAQLKTELLPLELLDQLQRFEQEAGRVRLRHWGERTLDLDLLIYGNEKIQNERLTVPHVGILQRDFVVIPLLDLDADLHINDQPLKNLELIQQPTLTVLADESWA 5ETS Chain:B ((5-138)) --IQAYLGLGSNIGDRESQLNDAIKILNEYDGISVSNISPIYETAPVGYTEQPNFLNLCVEIQTTLTVLQLLECCLKTEECLHRIRKERWGPRTLDVDILLYGEEMIDLPKLSVPHPRMNERAFVLIPLNDIAANV---------------------------

General information: TITO was launched using: RESULT: Template: 5ETS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 653 -26081 -39.94 -199.09 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain B : 0.76 3D Compatibility (PKB) : -39.94 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.603

(partial model without unconserved sides chains): PDB file : Tito_5ETS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5ETS-query.scw PDB file : Tito_Scwrl_5ETS.pdb: