Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKVQVKLLDPRLGKEWPLPSYATAGSAGLDLRACLDEAIEIEPGQTVLVKTGMAIYIHDVNFAGLILPRSGLGHKHGIVLGNLVGLIDSDYQGELMVSVWNRGQTTFRLEPGERLAQYVLVPVVQAEFEQVEEFEETLRGAGGFGHTGKQ 2OKD Chain:C ((22-131)) ------------------PTRQSPGAAGYDLYSAYDYTIP--PGERQLIKTDISMSMPKFCY-GRIAPRSGLSLK-GIDIGG--GVIDEDYRGNIGVILINNGKCTFNVNTGDRIAQLIYQRIYYPELEEVQSL----------------

General information: TITO was launched using: RESULT: Template: 2OKD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 440 -67175 -152.67 -610.68 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain C : 0.77 3D Compatibility (PKB) : -152.67 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.405

(partial model without unconserved sides chains): PDB file : Tito_2OKD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2OKD-query.scw PDB file : Tito_Scwrl_2OKD.pdb: