Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSCYLITGGAGFIGSTLANHLG-EEH------VVIVVDDLSMGKV-ENL---DMTKNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMILELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYCHLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSRDFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELT-LEYKEERSGDIHDSLADITKIQS-IGYQPKYGILSGMTNYLKTEIN 1R6D Chain:A ((1-312)) -MRLLVTGGAGFIGSHFVRQLLAGAYPDVPADEVIVLDSLTYAGNRANLAPVDADPRLRFVHGDIRDAGLLAREL--RGVDAIVHFAAESHVDRSIAGASVFTETNVQGTQTLLQCAVDAG--VGRVVHVSTNQVYGSIDSGSWTESSPLEPNSPYAASKAGSDLVARAYHRTYGLDVRITRCCNNYGPYQHPEKLIPL--------FVTNLL-DGGTLPLYGDGANVREWVHTDDHCRGIALVLAG-GRAGEIYHIGGGLELTNRELTGILLDSLGADWSSVRKVADRKGHDLRYSLDGGKIERELGYRPQVSFADGLARTVRWYR-

General information: TITO was launched using: RESULT: Template: 1R6D.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1748 -19448 -11.13 -65.04 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -11.13 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.498

(partial model without unconserved sides chains): PDB file : Tito_1R6D.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1R6D-query.scw PDB file : Tito_Scwrl_1R6D.pdb: