Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGK------NP-ILVGILKGSIPFMAELVKHI---DTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDIIDTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDYKENYRNLPYIGVLKEEVYSN 1P17 Chain:C ((9-191)) ------EKILFTEEEIRTRIKEVAKRIADDYKGKGLRPYVNPLVLISVLRGSFMFTADLCRALCDFNVPVRMEFICVSSYGE---SSGQVRMLLDTRHSIEGHHVLIVEDIVDTALTLNYLYHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDYDDTYRELRDIVVLRPEVYA-

General information: TITO was launched using: RESULT: Template: 1P17.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 805 248 0.31 1.46 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain C : 0.81 3D Compatibility (PKB) : 0.31 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.624

(partial model without unconserved sides chains): PDB file : Tito_1P17.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1P17-query.scw PDB file : Tito_Scwrl_1P17.pdb: