Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTAIANNHVVSFHYKLTNAEGETLDQSQGEPLAYLHGAGNIIPGLENALTGKTVGDKFTVNVPAAEGYGEYNPDLVQEVPAQMFQGVDNIQPGMQFQAQTDDGVQIVTVKAVEGDNVIVDANFPLAGQDLTFEVEIVEIREASQEELDHGHVHGAGGHHH 4ODQ Chain:A ((2-103)) --KVGQDKVVTIRYTLQV-EGEVLDQ---GELSYLHGHRNLIPGLEEALEGREEGEAFQAHVPAEKAYGATGHP---------------------------------------------------PHATLDFQVEVVKVREATPEELLHGHAHPS-----

General information: TITO was launched using: RESULT: Template: 4ODQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 450 -43866 -97.48 -447.61 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -97.48 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.641

(partial model without unconserved sides chains): PDB file : Tito_4ODQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ODQ-query.scw PDB file : Tito_Scwrl_4ODQ.pdb: