Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEIRSDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHY 1A09 Chain:B ((9-91)) WYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYY

General information: TITO was launched using: RESULT: Template: 1A09.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 305 -38342 -125.71 -461.95 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain B : 0.93 3D Compatibility (PKB) : -125.71 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.93 QMean score : 0.400

(partial model without unconserved sides chains): PDB file : Tito_1A09.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1A09-query.scw PDB file : Tito_Scwrl_1A09.pdb: