Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRPFLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFGEAMAILAGDALFLDPYALIAQADL-PSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ--HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVLDVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQVPFETESIVSVVESLRING 3LVS Chain:B ((10-284)) ----EIQDAVETAMAAAIGRL-PAGDLRDAMAYAA-QGGKRLRAFLAIESAAIHGISMAQA-MPAALAVEALHAYSLVHDDMPCMDNDDLRRGLPTVHKKWDDATAVLAGDALQTLAFELCTDPVLGSAENRVALVAALAQASGAEGMVYGQALDIAAETAAVPLTLDEIIRLQAGKTGALISFAAQAGAILAGADR---GPLTAYATALGLAFQIADDILDVE------------DAEAHKATFVSLLGLAGAKSRAADLVAEAEAALAPYGEA----ASTLRACARY-----

General information: TITO was launched using: RESULT: Template: 3LVS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1274 -106768 -83.81 -410.65 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain B : 0.78 3D Compatibility (PKB) : -83.81 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.494

(partial model without unconserved sides chains): PDB file : Tito_3LVS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3LVS-query.scw PDB file : Tito_Scwrl_3LVS.pdb: