Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKQLTVDEAAKEILAY--QQITFLTGAGVSTPSGVPDYRSL-SGIYHGMEQ-----PEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIH--LEIAHLAKEKNVWVVSQNIDGLHAKAKSP--QLVNFHGSLYQCHCRKCQQTV---DWKEYLHSD---KHQACGGQIRPDIVLYGEGFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEPYTFIQEDGAVVFKKIQELGADYD 5D7N Chain:A ((8-231)) --KLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLH-DKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVV-DFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINR-------------------------------

General information: TITO was launched using: RESULT: Template: 5D7N.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 940 -11330 -12.05 -55.00 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : -12.05 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.487

(partial model without unconserved sides chains): PDB file : Tito_5D7N.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5D7N-query.scw PDB file : Tito_Scwrl_5D7N.pdb: