Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKALITGITGQDGSYLAEFLLEKGYEVHGITRRASISNTAHIDHLMGKITLHDGDLSDSSSLIRIISIVQPDEIYNLAAQSHVQVSFDVPEYSGDVDALGVLRILEACRILGLTKKTKVYQASTSELYGKVEEVPQRETTPFHPYSPYAVAKQYGFWITKEYREAYGMFAVNGILFNHESERRGENFVTRKITLAAGRIAEGLQDHLELGNMDSLRDWGYAKDYVECMWMILQHETPEDFVIATGEQHTVRDFTEKAFAANGITIRWEGTGID--EKGYDV--------ETGKMLVCVNPQWFRPTDVDNLWGDPTKAKTVLGWNPQKTSYEELVSIMAKHDRELAKREAALKKASDLIE 1DB3 Chain:A ((1-357)) SKVALITGVTGQDGSYLAEFLLEKGYEVHGIKR--------------PKFHLHYGDLSDTSNLTRILREVQPDEVYNLGAMSHVAVSFESPEYTADVDAMGTLRLLEAIRFLGLEKKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVAKLYAYWITVNYRESYGMYACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYLGNMDSLRDWGHAKDYVKMQWMMLQQEQPEDFVIATGVQYSVRQFVEMAAAQLGIKLRFEGTGVEEKGIVVSVTGHDAPGVKPGDVIIAVDPRYFRPAE-ETLLGDPTKAHEKLGWKPEIT-LREMVSEMVANDLEAAKKHS----------

General information: TITO was launched using: RESULT: Template: 1DB3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1838 -75124 -40.87 -231.15 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.85 3D Compatibility (PKB) : -40.87 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.85 QMean score : 0.387

(partial model without unconserved sides chains): PDB file : Tito_1DB3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1DB3-query.scw PDB file : Tito_Scwrl_1DB3.pdb: