Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIIIQRVKKAQVSI-EGQIQGKINQGLLLLVGVGPEDQEEDLDYAVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMASDFY----DAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR 3KO4 Chain:D ((1-157)) MRVVIQRVKGAILSVR-LEIISEIKNGLICFLGIHKNDTWEDALYIIRKCLNLRLWNNDNKTWDKNVKDLNYELLIVSQFTLFGNTKKGNKPDFHLAKEPNEALIFYNKIIDEF-KKQYNDDKIKIGKFGNYMNIDVTNDGPVTIYIDT---

General information: TITO was launched using: RESULT: Template: 3KO4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 645 -9390 -14.56 -66.13 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain D : 0.83 3D Compatibility (PKB) : -14.56 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.461

(partial model without unconserved sides chains): PDB file : Tito_3KO4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3KO4-query.scw PDB file : Tito_Scwrl_3KO4.pdb: