Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIR----KCADTFLLARDENQLLGYILSSPQS---DNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAVELDYKGIRLESPDE-LLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ 3T9Y Chain:A ((4-145)) --MSIITRLFNNSDFEKLNQLCKLYDDLGYPTNENDLKKRLKKITNHDDYFLLLLIKENKIIGLSGMCKMMFYEKNAEYMRILAFVIHSEFRKKGYGKRLLADSEEFSKRLNCKAITLNSGNRN--------GYVSNTSG----------------------

General information: TITO was launched using: RESULT: Template: 3T9Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 457 24681 54.01 202.30 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 54.01 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.451

(partial model without unconserved sides chains): PDB file : Tito_3T9Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3T9Y-query.scw PDB file : Tito_Scwrl_3T9Y.pdb: