Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGINIENASFGLTNCAERTAFFKAVSEGE--KTFTHLVVAGHTPDPISPCGACRQVMAEFCSPDMPVTLVGDNGVTKATTVRALLPYAFTEKDL 3DMO Chain:A ((10-137)) ---THHALIEAAKAAREKAYAPYSNFKVGAALVTNDGKVFHGCNVENASYGLCNCAERTALFSALAAGYRPGEFAAIAVVGETHGPIAPCGACRQVMIELGKPTLEVVLTNMQGDVRVTSAGDLLPDAFYL---

General information: TITO was launched using: RESULT: Template: 3DMO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 679 -32097 -47.27 -254.73 target 2D structure prediction score : 0.75 Monomeric hydrophicity matching model chain A : 0.82 3D Compatibility (PKB) : -47.27 2D Compatibility (Sec. Struct. Predict.) : 0.75 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.562

(partial model without unconserved sides chains): PDB file : Tito_3DMO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3DMO-query.scw PDB file : Tito_Scwrl_3DMO.pdb: