Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQEEPSPSWSMRGLRKWLGTAPETRDELLKLVQNSRRFLEPDTVAMLEGVLDLPATKIREVMTPRTAMISMQEDDQLLDILHVLVESAHSRFPVFSADQPDNVVGILLAKDLLP-FLTEPNTKLDIGSLMRQPLFVPESARSDQVLRMLKHTQTHIAIVIDEYGSTAGLVTLEDILEEIVGEIEDEHDTADEDAQYIVPDNDHTIANAWMVQALTPIEHFNTVLDADFSDDEVETVGGLLLQEIGLVSDLQGQTVELGNWLFTIVEADARTIHLIRAVRQ 3OCM Chain:A ((27-166)) ----------------------------------------------VSGVLTLAERSIRSIMTPRTDVSWVNIDDDAATIRQQLTAAPHSFFPVCRGSL-DEVVGIGRAKDLVADLITEGRVRRN---RLRDPIIVHESIGILRLMDTLKRSRGQLVLVADEFGAIEGLVTPIDVFEAIAGEFPDEDELP------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3OCM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 575 -60355 -104.96 -434.21 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -104.96 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.399

(partial model without unconserved sides chains): PDB file : Tito_3OCM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3OCM-query.scw PDB file : Tito_Scwrl_3OCM.pdb: