Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIKLIRADQYTKMLWKNGAGFTLEIARSQ--GEADFEWRISMADVTTSGPFSLFPNKQRIISVLDGQGMVLHVDDLPAKKLKQGDIFAFHGESQVQSELVDGAIRDLNLIYDPAKFHARFQWLNEAAEQAFISSADLIFIFNQGDETEVNVDEH-SVQLAAHETLKIEKKSGVTSINFPKKQFKCCYIIELIQR 1YLL Chain:A ((3-195)) ELRILRAVDYPRMP-----GSTEEIARDGGDGLDGFGWRLSIADVGESGGFSGFAGYQRIISVLEGGGMRLRVDGAESAPLRARQAFAFSGDSEVHCTLLDGAIRDFNLIYAPRRHRARLQWLRVEGELDWHGTASTLLLFAQQDGVAISLQGQPRGQLAAHDCLCAEGLQGLQHWRLTAHEPAWVCAVELDS-

General information: TITO was launched using: RESULT: Template: 1YLL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 968 -17774 -18.36 -96.07 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -18.36 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.464

(partial model without unconserved sides chains): PDB file : Tito_1YLL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1YLL-query.scw PDB file : Tito_Scwrl_1YLL.pdb: