Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTQRCGWCSDDPLYIAYHDEEWGKPEHDEARLFEMLCLEGQQAGLSWITVLKKRESYRQHFFNHPIADIAAFTDDFLETKLSDAGLIRHLGKLKAIRDNAIAWQALKAQVDDVSKWLWQFVDAAPQNNDVVDYRKAPAQTEL---SLKLSKTLKKNGFKFVGPTTCYAFMQAVGMVNDHENNCQFKAS 2JG6 Chain:A ((3-182)) ----ECAFGTKDPVYLNYHDHVWGQPLYDSKALFKLLALESQHAGLSWLTILKKKEAYEEAFYDFEPEKVAQMTAQDIDRLMTFPNIVHHRKKLEAIVNQAQGYLKIEQAYGSFSKFLWSYVNGKPKD---LQYEHASDRITVDDTATQLSKDLKQYGFKFLGPVTVFSFLEAAGLYDAHLKDCPSK--

General information: TITO was launched using: RESULT: Template: 2JG6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 780 -57391 -73.58 -324.24 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.83 3D Compatibility (PKB) : -73.58 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.469

(partial model without unconserved sides chains): PDB file : Tito_2JG6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2JG6-query.scw PDB file : Tito_Scwrl_2JG6.pdb: