Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MADFKAKEILLNAFDMNCVGHINHGLWTHPRDESHRFNELSYWTEQAKTLENGLFDGLFIADITGVYDVYQNGIDLTLKESIQLPSHDPSTLISAMAAVTQNLSFGVTVNLSYEHPYQFARRFASLDHLTQGRIGWNIVTGYLDSAERLIGQKGLKDHDARYEQAEEFLELCYKYWEGSWENDAVKKDKARRVFTDP-SKVHTIHHHGKYYQSEGVFQVSPSVQRTPTLFQAGASPKGMQFATRHAECVF-IGGDKPEKIREQVKKIRTLAEQQGRSANDIKVFVGITVVVAETHDLAVQKLNEYRQYASP-EAGLAHYASSTGIDLSKFADDEA-------IPYQKSNSI--------VSITEKFKEQQITKNDLKAQHVLGGRYPLIVGSGEEVAEYLIHLLDETDIDGFNLTRTVAPESHHDFIRLVIPELQQHGRYKTAYKTGSLRNKIFNRGDHLPEQHPVQAFRCSPYNNSKNLTKIEEITA 5DQP Chain:A ((12-422)) ---------------LNSSGVLPNS-WNEGRGNRARIFDLENYIRSAEIARRGRIDAFFLAD--------QPQLTPNPKVRPEYP-FDPIVLAAAITGRVPDIGGIVTASTSFSLPYTLARQIASVNLLSGGRIGWNAVTTANPAVAANYG-AAIATHDNRYERAEEFLEVVHGLWN-SWK---FPWDEAIGPNPNPFGEVMPINHEGKYFKVAGPLNVPLPPYGPPVVVQAGGSDQGKRLASRFGEIIYAFLGSKPAGRRFVAEARAAARAQGRPEGSTL-VLPSFVPLIGSTEAEVKRLVAEYEAGLDPAEQRIEALSKQLGIDLERINVDQVLQEKDFNLPKESATPIGILKSMVDVALDEKLSLRQ-----------LALRMRLIAGTPDQVADRLIDWWQDEAADGFVINAPLLPDALEIFVDQVVPILQSRGVFPRSYTESTLRERL-----------------------------------

General information: TITO was launched using: RESULT: Template: 5DQP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1942 -37080 -19.09 -94.35 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -19.09 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.436

(partial model without unconserved sides chains): PDB file : Tito_5DQP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5DQP-query.scw PDB file : Tito_Scwrl_5DQP.pdb: