Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPAVKSNRPVNLSMGQVLAVNLRSPV-AIASILHRLSGVIVFLLVPVLLWILDKSLSSPEGFDYVKNVVFGNILVRFVVWVFVAGLIFHFIAGVKHLLADLGFAEE-LQSGRIAATISLILSVVAIIAAFVWIVF 2WP9 Chain:C ((8-119)) ------QRPVNLDLQ-----TIRFPITAIASILHRVSGVITFVAVGILLWLLGTSLSSPEGFEQA-SAIMGSFFVKFIMWGILTALAYHVVVGIRHMMMDFGYLEETFEAGKRSAKISFVITVV-----------

General information: TITO was launched using: RESULT: Template: 2WP9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 231 -37995 -164.48 -345.41 target 2D structure prediction score : 0.75 Monomeric hydrophicity matching model chain C : 0.79 3D Compatibility (PKB) : -164.48 2D Compatibility (Sec. Struct. Predict.) : 0.75 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.232

(partial model without unconserved sides chains): PDB file : Tito_2WP9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2WP9-query.scw PDB file : Tito_Scwrl_2WP9.pdb: