Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIATFNKSKTALTINRQEFKLALGKIDAGIEKQIVSLKKAKQSYNAAEMAR--EVISEANIFEAIIEGF---NEAEGTNLKL-----ADITN----LEVAQGWIDDFLEKYSEV 3DYL Chain:A ((185-247)) ---------------------------------------------ATDMARHAEIMDS---FKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEY---

General information: TITO was launched using: RESULT: Template: 3DYL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 91 10936 120.17 223.17 target 2D structure prediction score : 0.41 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : 120.17 2D Compatibility (Sec. Struct. Predict.) : 0.41 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.304

(partial model without unconserved sides chains): PDB file : Tito_3DYL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3DYL-query.scw PDB file : Tito_Scwrl_3DYL.pdb: