Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVAGLTNGELIAPMTYEEMVTSDFFEAWFQKFLLPTLT-----TPSVIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPEYNP-IEKTWAYIKKNLKKVLPSCNTFYEALFSCSCFN 3HPH Chain:A ((97-178)) -----------------------------QEFRVQTMKWYAMFAPKSLQSDNGPAFVAESTQLLMKYLGIEHTTGIPWNPQSQALVERTHQTLKNTLEKLIPMFNAFESAL-------

General information: TITO was launched using: RESULT: Template: 3HPH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 145 7223 49.81 95.03 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : 49.81 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.396

(partial model without unconserved sides chains): PDB file : Tito_3HPH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3HPH-query.scw PDB file : Tito_Scwrl_3HPH.pdb: