Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAALAAAGGGGLQLVL--ASYGLRSALVAGIVKGLGVL--GIHIGNAFANTVIRSIASAGIGAGADWIFTNIIDGWDGRRDNQLRIG 1GPE Chain:A ((285-360)) --------------------------------------AKHEVLLAAGSAISPLILEYSGIGLKSVLDQANVTQLLDLPVGINMQDQTTTTVSSRASSAGAGQGQAVFFANFTE-------------

General information: TITO was launched using: RESULT: Template: 1GPE.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 119 -9527 -80.06 -132.32 target 2D structure prediction score : 0.22 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -80.06 2D Compatibility (Sec. Struct. Predict.) : 0.22 1D Compatibility (Hydrophobicity) : 0.63 QMean score : -0.024

(partial model without unconserved sides chains): PDB file : Tito_1GPE.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1GPE-query.scw PDB file : Tito_Scwrl_1GPE.pdb: