Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNLKSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA 1RZR Chain:T ((2-86)) -AQKTFTVTADSGIHARPATTLVQAASKFDSDINLEFNGKTVNLKSIMGVMSLGIQKGATITISAEGSDEADALAALEDTMSKEGL-

General information: TITO was launched using: RESULT: Template: 1RZR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain T - contact count / total energy / energy per contact / energy per residue : 380 -54539 -143.52 -641.63 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain T : 0.91 3D Compatibility (PKB) : -143.52 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.91 QMean score : 0.668

(partial model without unconserved sides chains): PDB file : Tito_1RZR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1RZR-query.scw PDB file : Tito_Scwrl_1RZR.pdb: