Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIGLLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRKVEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAFVVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLSLVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQGNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM 2L6W Chain:B ((28-37)) -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LIMLWQKKPR--

General information: TITO was launched using: RESULT: Template: 2L6W.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2 227 113.25 22.65 target 2D structure prediction score : 0.20 Monomeric hydrophicity matching model chain B : 0.38 3D Compatibility (PKB) : 113.25 2D Compatibility (Sec. Struct. Predict.) : 0.20 1D Compatibility (Hydrophobicity) : 0.38 QMean score : 0.365

(partial model without unconserved sides chains): PDB file : Tito_2L6W.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2L6W-query.scw PDB file : Tito_Scwrl_2L6W.pdb: