Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MWYNCKRFNPIIYKERKIFMRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAFPD--LIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQAESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSEKYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFMEVDKDSFN-DQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESLFMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEIENKDNLIWHLHNTAHLYRQELFTE-FILFDQKGNTIRNFQNIFPKFVSDVKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHLVINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSPYDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE 4R6I Chain:B ((4-476)) -----------------MLTPISIEKEHIRLINLLHFINEQNRWFTIKELSDYLQVADKTVRKYLKLLEDEIPPSWNLLVQKGKGIYLKKPLNESLSFVESKILRKSLNLQICEELVFKK-NSMQSLAQKLHLQVGALYPIINQINYDI-QSSHLNIKKKPLEISGREQDVRVFMLRLYCNI-PNDYWPFPYINKQNITDLINKMEKILNVQMYTYSKHKLCVLFAITISRLLSGNTIDNVSGLILVNKNDDHYK---TVASITSELQNSFGVTLHETEISFLALALLLSLGNSIT---NK-T-LTSYKKTIMPLAKEITKGIEHKLQLGINYDESFLTYVVLIIK---KALDKNFIQYYNYNIKFIRHIKQRHPNTFNTIQECISNLNYTVYSH-----FDCYEISLLTMHFETQRML-FKNNPKKIYVYTSQGCIHREYISALLEKRYNGLIKIVRNTI---------DMEIDIIISN---------------EFPTERDFHEIKK--------

General information: TITO was launched using: RESULT: Template: 4R6I.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1892 -54094 -28.59 -122.11 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain B : 0.67 3D Compatibility (PKB) : -28.59 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.516

(partial model without unconserved sides chains): PDB file : Tito_4R6I.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4R6I-query.scw PDB file : Tito_Scwrl_4R6I.pdb: