Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGDYLMNMLANISFDAAVFTSLEVMNVGVEDGVVKFSLSVQNAEHIYIVASVKGIEKNDTFEYGEGLDYQDWKDVDYTMMTVDSSSRPHVDHFDYVDAIEGMPFALTSTQILKLNEYLEELAREEKINELRGGWWELDI 4V38 Chain:A ((301-355)) ----ITNIPANISFEILMMTGLLPDKVGGVASSLYFSLPKEKISHIIFTSNKKIKNKED--------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4V38.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 109 -9878 -90.62 -179.60 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : -90.62 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.60 QMean score : -0.038

(partial model without unconserved sides chains): PDB file : Tito_4V38.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4V38-query.scw PDB file : Tito_Scwrl_4V38.pdb: