Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSSTILVIHGPNLNLLGKREPEVYGHLTLDNINQQLIAQAEQASITLDTFQSNWEGAIVDRIHQAQTEGVKLIIINPAALTHTSVALRDALLGVAIPFIEVHLSNVHAREAFRHHSYLSDKAIGVICGLGAKGYSFALDYAIEKIQPSNPN 4L8L Chain:A ((3-145)) ---TLLVLHGPNLNLLGT-------STTLGQINQDLERRAREAGHHLLHLQSNAEYELIDRIHAARDEGVDFIIINPAAFTHTSVALRDALLAVSIPFIEVHLSNVHKREPFRHHSYFSDVAVGVICGLGATGYRLALESALEQLQ-----

General information: TITO was launched using: RESULT: Template: 4L8L.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 667 -130712 -195.97 -961.12 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.88 3D Compatibility (PKB) : -195.97 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.88 QMean score : 0.572

(partial model without unconserved sides chains): PDB file : Tito_4L8L.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4L8L-query.scw PDB file : Tito_Scwrl_4L8L.pdb: