Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNNQITLAYLDYDDLDALQVV--SVVSFYE-SFIDGADPLDMQGYLQTQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLGQRLL----DEANRYAKTNKNVIYV 1QSM Chain:A ((3-114)) --DNITVRFVTENDKEGWQRLWKSYQDFYEVSFPDDLDDFNFGRFLDPNIKM-WAAVAVESSSEKIIGMIN---FFNHMTTWDFKDKIYINDLYVDENSRVKGAGGKLIQFVYDEADK-----------

General information: TITO was launched using: RESULT: Template: 1QSM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 403 17134 42.52 163.18 target 2D structure prediction score : 0.34 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : 42.52 2D Compatibility (Sec. Struct. Predict.) : 0.34 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.290

(partial model without unconserved sides chains): PDB file : Tito_1QSM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1QSM-query.scw PDB file : Tito_Scwrl_1QSM.pdb: