Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNFDRNTPIAFLGIGLMGNRMASHLIQAGFQVAVWNRTASACEELID-IGAHALDLS-NIGQYPLILTCLADDKAVQAVFDQIQTNLKAGQVIVDFSSLSVAATKALAQAAALQDVIWIDSPVSGGTAGAEQGTLVIFAGGDAQTIEALSPVYNVLSQRVTRMGDTGTGQATKICNQLIVAANSALIAEAVALADRAGVDTTLLAPALAGGFADSKPFQILA-PRMATHTFEPVQWKVQTLSKDLNNAVTLANNVNLDIPVAQKALLQLQTHQKNSFAEKDLATMIQVVEQ 2CVZ Chain:C ((1-282)) -----MEKVAFIGLGAMGYPMAGHLAR-RFPTLVWNRTFEKALRHQEEFGSEA-VPLERVAEARVIFTCLPTTREVYEVAEALYPYLREGTYWVDATSGEPEASRRLAERLREKGVTYLDAPVSGGTSGAEAGTLTVMLGGPEEAVERVRPFLA-YAKKVVHVGPVGAGHAVKAINNALLAVNLWAAGEGLLALVKQGVSAEKALEVINASSGRSNATENLIPQRVLTRAFPKT-FALGLLVKDLGIAMGVLDGEKAPSPLLRLAREVYEMAKRELGPDADHVEALRLLER

General information: TITO was launched using: RESULT: Template: 2CVZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1513 -21928 -14.49 -78.59 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain C : 0.75 3D Compatibility (PKB) : -14.49 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.539

(partial model without unconserved sides chains): PDB file : Tito_2CVZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2CVZ-query.scw PDB file : Tito_Scwrl_2CVZ.pdb: