Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVIDFKQDILAPVATDFAAMDHLINEGISSKVGLVMSVSKHVVEAGGKRMRPIMCLLAARACGLDNMQNAQRLAAIIEMLHTATLVHDDVVDESGLRRGRPTANATWNNQTAVLVGDFLIARAFDLLVDLNNMTLLKDFSTGTCEIAEGEVLQLQSQHQPDTTEETYLKIIHGKTSRLFELATEGAAILAGQEA-YREPLRLFAGHFGNAFQIIDDILDYTSDAETLGKNIGDDLMEGKPTLPLISALAHSTGEEHA---IIRRSIATGGVDQLPKVIEIVQKSGALDYCQRRAQEETEAALQALSILPDTPYRQALINLTRLALHRIQ 4JYX Chain:G ((22-344)) --SMDLDHILSLAEPDMLAVNQLIQKQVNSDVSLINQLGFYIVNSGGKRLRPLLTVLAARALNIQT-EQHHTLAAIIEFIHTATLLHDDVVDESTMRRGRETANEVFGNQASVLVGDFLYTRSFQMMVTLDSMRVMQILSDATNVIAEGEVLQLMNCNDPDTTEESYMEVIYSKTARLFEAATLLAGVLTKQSEAIENAMQDYGKYLGTAFQLVDDIMDYAS-------NMGDDLAEGKPTLPLLYAMWHGNEQQTAIIREAIETG--NGMDNLTPILETMEQTGALTYTKQQALKASQQAIDALSPIEESVYKEALIGLAHISVERV-

General information: TITO was launched using: RESULT: Template: 4JYX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain G - contact count / total energy / energy per contact / energy per residue : 1533 -147137 -95.98 -471.59 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain G : 0.85 3D Compatibility (PKB) : -95.98 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.85 QMean score : 0.485

(partial model without unconserved sides chains): PDB file : Tito_4JYX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4JYX-query.scw PDB file : Tito_Scwrl_4JYX.pdb: