Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQLTLVRHGEAAPPVNGNDIKRPLTARGHAQAEQTATFLKDIV-KPNIFVVSPLLRAQETLAHIQTYFKDVPVLLCDKIKPDDDAKEAIEW-LSQ--I-PYESIVVVCHMNVVGHIAELLTHET---FNPFALAEARIYDQAVI--ANGLSTQKNSFIPTI 3F2I Chain:A ((1-162)) MELYLIRHGIAEAQ--IKDEERELTQEGKQKTEKVAYRLVKLGRQFDLIVTSPLIRARQTAEILLASGLSCQLEESNHLAPNGNIFNWLDYWLKPKNFPENAQIAIVGHEPCLSNWTEILLWGEAKDSLVLKKAGMIGLKLPEIGSPVGRSQMFWLTPPRY

General information: TITO was launched using: RESULT: Template: 3F2I.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 752 -26218 -34.86 -175.96 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -34.86 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.393

(partial model without unconserved sides chains): PDB file : Tito_3F2I.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3F2I-query.scw PDB file : Tito_Scwrl_3F2I.pdb: