Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MATIDLPDNLVQTLSLVLNQLQQVLPEPKQETDFTAPAFRWENQQLKAIYTPKNIYLDDLKGIERQKEKIIQNTLQFL--------NGLPANDVLLTGSRGTGKSSIVRALLTEYAPQGLRLIEIERDDLA---------DLPKIQKIIQNRPEKYIVYCDDLAFNAEDE--NYRSLKSVLDGSLQ-SGSTNFIIYATSNRRHLLPEFMHENTPVTKVDVPQYTELHPQEAIEEKISLSDRFGLWLSFYPMDQNLYLEIVEHYLDKANMPFNDEVRAESLRWCQMRGQRSGRAAYQFSKHWIGLNALKDLSNN 3KDS Chain:E ((11-215)) ----------------------------------------------------KRVTFKDVGGAEEAIEELKEVVEFLKDPSKFNRIGARMPKGILLVGPPGTGATLLARAVAGEA---NVPFFHISGSDFVELFVGVGAARVRDLFAQAKA-HAPCIVFIDEIDAVGRH-DEREQTLNQLLVEMDGFDSKEGIIVMAATNRPDILDPALLR---------------------------PGRFDKKIVVDPPDMLGRKKILEIHTRNKP---------------------------------------------

General information: TITO was launched using: RESULT: Template: 3KDS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain E - contact count / total energy / energy per contact / energy per residue : 833 14519 17.43 88.53 target 2D structure prediction score : 0.78 Monomeric hydrophicity matching model chain E : 0.63 3D Compatibility (PKB) : 17.43 2D Compatibility (Sec. Struct. Predict.) : 0.78 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.420

(partial model without unconserved sides chains): PDB file : Tito_3KDS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3KDS-query.scw PDB file : Tito_Scwrl_3KDS.pdb: