Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYHGMEQPEYLLSHQAMVNEPDKFYQFVKKIY--HPEAKPNIIHLEIAHLAKE-KNVWVVSQNIDGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEY------LHSDKHQACGGQIRPDIVLYGEGFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQP-SAKILVINQTPVYLAE-PYTFIQEDGAVVFKKIQELGADYD 1YC5 Chain:A ((2-243)) ----KMKEFLDLLNESRLTVTLTGAGISTPSGIPDF-------------QNVFDIDFFYSHPEEFYRFAKEGIFPMLQAKPNLAHVLLAKLEEKGLIEAVITQNIDRLHQRAGSKKVIELHGNVEEYYCVRCEKKYTVEDVIKKLESSDVPLCDDCNSLIRPNIVFFGENLPQDALREAIGLSSRASLMIVLGSSLVVYPAAELPLITVRSGGKLVIVNLGETPFDDIATLKYNMDVVEFARRVMEEG----

General information: TITO was launched using: RESULT: Template: 1YC5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1170 -43133 -36.87 -196.06 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -36.87 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.542

(partial model without unconserved sides chains): PDB file : Tito_1YC5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1YC5-query.scw PDB file : Tito_Scwrl_1YC5.pdb: