Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPVRLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADETAV------------PAGGALAVDRDSFSETITRKVKEHPLVTVIN------------------EEITEIPEGITVVATGPLTSH---------PLAESIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKG-----------EAAYLNCPMTEEEFKAFHEALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYAVIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSPELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQ-ETAIGSMAYYITH------------A-----------EGKHFQPMNANYGLFPELPE-RIRDKKARYEAIAQRALKANEAIKTELEKTAIPNE 3G05 Chain:A ((25-506)) ----------QGSFYPDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTL---------GQMSCNPAIGGI----GKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRVLYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDSIPLSRRLRE-LPLRVGRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMGNASQHPQQVPCYIT--HTNEKTHDVIRSNLDRSP-----------PSIED------KVMRFA-------------DRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENAKIVRPGYAIEYDFFDPR-DLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAARLSDDKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTEIGRELGLVDDERWARFNEKLENIERERQRL-------------------

General information: TITO was launched using: RESULT: Template: 3G05.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2383 12051 5.06 31.55 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 5.06 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.316

(partial model without unconserved sides chains): PDB file : Tito_3G05.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3G05-query.scw PDB file : Tito_Scwrl_3G05.pdb: