Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGRKTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAVYQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQRNENPVKSGTGELTI 3JVX Chain:B ((14-168)) ------AMDENRVIGKDNNLPWRLPSELQYVKKTTMGHPLIMGRKNYEAIG-RPLPGRRNIIVTRNEGYHVEGCEVAHSVEEVFELCKNEEEIF-IFGGAQIYDLFLPYVDKLYITKIHHAFEGDTFFPEMDMTNWKEVFVEKGLTDEKNPYTYYYHVYEKQQ------------

General information: TITO was launched using: RESULT: Template: 3JVX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 661 -81034 -122.59 -522.80 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain B : 0.79 3D Compatibility (PKB) : -122.59 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.529

(partial model without unconserved sides chains): PDB file : Tito_3JVX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3JVX-query.scw PDB file : Tito_Scwrl_3JVX.pdb: