Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MATIDLPDNLVQTLSLVLNQLQQVLPEPKQETDFTAPAFRWENQQLKAIYTPKNIYLDDLKGIERQKEKIIQNTLQFLN---------GLPANDVLLTGSRGTGKSSIVRALLTEYAPQGLRLIEIERDDLA---------DLPKIQKIIQNRPEKYIVYCDDLAFNAEDE-----------NYRSLKSVLDGSLQSGSTNFIIYATSNRRHLLPEFMHENTPVTKVDVPQYTELHPQEAIEEKISLSDRFGLWLSFYPMDQNLYLEIVEHYLDKANMPFNDEVRAESLRWCQMRGQRSGRAAYQFSKHWIGLNALKDLSNN 5E7P Chain:A ((480-672)) ----------------------------------------------------GSVTLDDVGDMVETKRALTEAVLWPLQHPDTFSRLGIDPPRGVLLYGPPGCGKTFVVRALASSG---RLSVHAVKGSELMDKWVGSSEKAVRELFARARD-SAPSLVFLDEIDALAPRRGQNFDSGVTDKVVASLLTELDGIE--PLRDVVVLGATNRPDLIDPALLR---------------------------PGRLERLVFVEPPDAAARRDILRTAGKSIPL--------------------------------------------

General information: TITO was launched using: RESULT: Template: 5E7P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 714 -2258 -3.16 -13.77 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -3.16 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.469

(partial model without unconserved sides chains): PDB file : Tito_5E7P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5E7P-query.scw PDB file : Tito_Scwrl_5E7P.pdb: