Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MINLVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCPAAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILP-MSFIPQGTDLLAITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYVLKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNILHETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNSGHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLE------SYRLIENKPDWQFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD 3AX6 Chain:C ((1-363)) ----------MKKIGIIGGGQLGKMMTLEAKKMGFYVIVLDPTPRSPAGQVADEQIVAGFFDSERIEDLVKGSDVTTYDLEHIDVQTLKKLYNEGYKIHPSPYTLEIIQDKFVQKEFLKKNGIPVPEYKLVKDLES---DVREFGFPVVQKARK-G----GVFIIKNEKDLENAIK----GETYLEEFVEIEKELAVMVARNEKGEIACYPVVEMY-------TVIAPARIEEKYSKIAREIATSVVEALEGVGIFGIEMFLTKQGEILVNEIAPRPHNSGHYTIEACVTSQFEQHIRAIMNLPLGSTELL-IPAVMVNLLGEEGYYGKPALIGLEEALAIEGLSLHFYGKKETRPYRKMGHFTVVDRDVERALEKALR-----

General information: TITO was launched using: RESULT: Template: 3AX6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1944 -48214 -24.80 -140.98 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain C : 0.80 3D Compatibility (PKB) : -24.80 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.543

(partial model without unconserved sides chains): PDB file : Tito_3AX6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3AX6-query.scw PDB file : Tito_Scwrl_3AX6.pdb: