Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKGMKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDH-DSVYQALKVSTPFAIETFAPNL-------ENFLEKYKENEARE-LEHPILFEGVSDLLEDILNQGGRHFLVSHRN-DQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQI--SSGLVIGDRPIDIEAGQAAGLDTHLFTSIVNLRQVLDI 1TE2 Chain:B ((7-199)) ---RQILAAIFDMDGLLIDSEPLWDRAELDVMASLGVDISRRNELPDTLGLRIDMVVDLWYARQPWNGPSRQEVVERVIARAISLVEETRPLLPGVREAVALCKEQGLLVGLASASPLHMLEKVLTMFDLRDSFDALASAEKLPYSKPHPQVYLDCAAKLGVDPLTCVALEDSVNGMIASKAARMRSIVVPAPEAQ------

General information: TITO was launched using: RESULT: Template: 1TE2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 902 -17048 -18.90 -94.19 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain B : 0.67 3D Compatibility (PKB) : -18.90 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.461

(partial model without unconserved sides chains): PDB file : Tito_1TE2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1TE2-query.scw PDB file : Tito_Scwrl_1TE2.pdb: